Dr. Ben Yudkoff, Co-Founder and Chief Medical Officer at Lumin Health, hosted a Reddit AMA on r/TherapeuticKetamine community on March 6th, 2026. The below blog post is a recap of one of the questions presented on that AMA, syndicated to the Lumin Health blog in the event that it answers any questions about ketamine therapy, Spravato treatment, or general concerns you may have about treatment.
Read the original Reddit AMA here
Don’t hesitate to get in touch with us if you’re interested in learning more about ketamine for depression at Lumin Health. Thank you once again to the moderators and community members for facilitating such an engaging discussion.
trikeAccordingly asks:
What can a patient do to prevent K-bladder?
Answer from Dr. Ben Yudkoff, Co-Founder and Chief Medical Officer of Lumin Health:
K-bladder, or ulcerative cystitis, is a condition that occurs when ketamine and its breakdown products – norketamine/hydroxynorketamine – irritate the lining of the bladder. Replace with italic/bold rich text: 'There are very few examples…' with 'very few' emphasized. when people are taking the medication in a medical protocol. There is one article published a couple of years back as a case report…. The incidence of ulcerative cystitis is very low when the exposure to ketamine/esketamine occurs in the context of a treatment protocol. That said, for people who are worried, I recommend hydrating after treatment – good for the body, in general, and also to help flush the bladder – and watching for symptoms.
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